Juliette Sabbatani Consulting

Elevating Discovery into Innovation, Strategizing Innovation into Therapy

From Hit to Lead to Drug Candidate: Medicinal Chemistry that Drives Impact

With nearly a decade of experience in small-molecule drug discovery, I support early-stage therapeutic programs through thoughtful design, clear strategy, and collaborative execution. My work spans the full discovery pipeline, helping teams navigate complexity and move confidently toward candidate nomination.

CHEMISTRY LEADERSHIP
I have led 7 drug discovery programs, with recognized expertise in CNS drug design.

  • Apply structure-based design, lead optimization, and asset selection to advance high-quality compounds

  • Collaborate closely with computational chemists, pharmacologists, and DMPK experts

  • Focus on delivering molecules with scientific rigor and clinical intent

END-TO-END DISCOVERY EXECUTION

  • Target validation and early feasibility

  • Target engagement and pharmacological confirmation

  • In vivo proof-of-concept

  • Build structured project plans with clear milestones and cross-functional coordination

INNOVATION WITH REAL WORLD RESULTS 

  • Co-inventor on 10 patents

  • Contributed to a program that reached Phase 2 clinical trials

  • Helped enable the launch of a new biotech company based on early discovery success

STRATEGIC INSIGHT AND DUE DILIGENCE

  • Provide clear, data-driven input on technical assessments and development strategies

  • Support opportunity evaluation, risk analysis, and go/no-go decisions

  • Help shape early-stage decisions that drive long-term value

Whether you're building a new program or strengthening an existing one, I bring the insight, execution, and strategy needed to turn early discovery into real therapeutic opportunity.

Translating Science into Strategy: Venture & BD Support

I help early-stage ventures, academic teams, and innovation hubs navigate the path from discovery to opportunity. Drawing on my experience in startup acceleration, scientific assessment, and cross-functional collaboration, I offer strategic support that bridges science and execution.

VENTURE & STARTUP ENABLEMENT

  • Support preclinical strategy, IP planning, and milestone definition
  • Coach teams on scientific storytelling, pitch development, and value creation
  • Contributed to the growth of startups including 9Bio Therapeutics, TATUM Bioscience, and RejuvenRx 

 

STRATEGIC ASSESSMENT & PARTNERSHIPS

  • Conduct technical assessments, opportunity evaluations, and due-diligence
  • Help define value propositions and support partnering conversations
  • Translate complex science into clear, compelling narratives for investors and collaborators

Let’s turn promising science into strategic momentum and measurable outcomes.

About me

Hi, I'm Juliette Sabbatani

I’m a medicinal chemist with nearly 10 years of experience in small-molecule therapeutics—advancing programs from hit identification to clinical candidate selection, while also supporting startup creation, partnerships, and strategic development.

 

At X-Chem and adMare BioInnovations, I’ve led medicinal chemistry efforts across multiple therapeutic areas and played key roles in early-stage biotech formation, due diligence, and asset evaluation. I’ve co-authored 10 patents and contributed to clinical-stage candidates through close collaboration with cross-functional teams.

 

French and Canadian, with a PhD from the University of Vienna and postdoctoral research at the Technion in Israel, I bring a strong international perspective and a deep understanding of the drug discovery landscape in both Europe and North America.

 

Curious, pragmatic, and highly adaptable, I’m known for solving complex problems and bridging science with strategy to move projects forward.


I’m always open to new ideas, partnerships, and conversations—let’s connect and see how we might work together.

Dr. Sabbatani helped to propel our drug development project to new heights.

I have learned a lot about drug development, interdisciplinary project management and IP from her during our collaborative project.

Anastassia Voronova, PhD

Associate Professor

University of Alberta

Juliette worked in my group at adMare and was a key lead on several projects.

One pain asset where she was key is now close to IND enabling studies.

A solid and dedicated medicinal chemist.

Joseph Mancini, PhD

Vice President of Research
adMare BioInnovations

Juliette collaborated on a multiparameter optimization project for a challenging target in the CNS. The project was successful in advancing to the next milestone. Her team had innovative ideas for synthesis and thoroughly analyzed data to help drive the next round of compound design.

Kristen Burford, PhD

Director of Medicinal Chemistry

Xenon Pharmaceuticals

Juliette brings creative ideas, good communication and consistent enthusiasm to collaborative efforts.  She is able to quickly digest and interpret new data to inform design hypotheses and synthesis execution. Those features enable meaningful program advancement.

Jason Crawford, PhD

EVP Drug Discovery

Gandeeva Therapeutics

Contact

Let’s connect and drive innovation together

pharmaconsult@juliettesabbatani.com

Montreal, Quebec, Canada